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论文题目: Immunomodulation of artemisinin and its derivatives
英文论文题目: Immunomodulation of artemisinin and its derivatives
第一作者: Yao, WB; Wang, F; Wang, H
英文第一作者: Yao, WB; Wang, F; Wang, H
联系作者: Wang, H (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Nutr Sci, Key Lab Food Safety Res, Shanghai 200031, Peoples R China.
英文联系作者: Wang, H (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Nutr Sci, Key Lab Food Safety Res, Shanghai 200031, Peoples R China.
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发表年度: 2016
卷: 61
期: 18
页码: 1399-1406
摘要: In the 1970s, artemisinin ("qinghaosu" in Chinese), a sesquiterpene lactone with an unusual peroxide bridge, was isolated from Artemisia annua L. It showed promising antimalarial activity, particularly by eliminating parasites resistant to chloroquine. For more than 30 years, artemisinin has contributed to worldwide health as a new type of antimalarial drug. Artemisinin and its analogs, such as dihydroartemisinin, artemether, artesunate, artemiside, artemisone, and arteether, possess not only potent antimalarial activity but also anti-viral, antifungal, anticancer, and anti-inflammatory properties. In this review, we discuss the current understanding of how artemisinin and its analogs affect the immune system and immune-related diseases.
英文摘要: In the 1970s, artemisinin ("qinghaosu" in Chinese), a sesquiterpene lactone with an unusual peroxide bridge, was isolated from Artemisia annua L. It showed promising antimalarial activity, particularly by eliminating parasites resistant to chloroquine. For more than 30 years, artemisinin has contributed to worldwide health as a new type of antimalarial drug. Artemisinin and its analogs, such as dihydroartemisinin, artemether, artesunate, artemiside, artemisone, and arteether, possess not only potent antimalarial activity but also anti-viral, antifungal, anticancer, and anti-inflammatory properties. In this review, we discuss the current understanding of how artemisinin and its analogs affect the immune system and immune-related diseases.
刊物名称: SCIENCE BULLETIN
英文刊物名称: SCIENCE BULLETIN
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学科: Multidisciplinary Sciences
英文学科: Multidisciplinary Sciences
影响因子: 4
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论文类别: Article
英文论文类别: Article
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